Vaccine rollout is a much-needed win for UK after bungling its pandemic response
Basingstoke, England (CNN)Last May, Steve Bates' phone rang. The UK was in the midst of its first national lockdown -- there was a stay-at-home order, schools and most shops were closed, and experts were warning that a vaccine could still be years out.
At the other end of the line was an old friend, Kate Bingham,
a pharmaceutical investor who had just agreed to lead the UK's Vaccine
Taskforce, a team of private sector experts assembled to secure vaccine
doses for the British public. She wanted him to join.
"She
wanted my contacts. She knew that I knew everybody in the industry,"
Bates, a lobbyist who heads the UK BioIndustry Association, told CNN.
"Kate Bingham said to me, 'we've never made a vaccine that's worked
against a human coronavirus. This is a long shot.'"
Compelled by a sense of national duty in a time of crisis, Bates agreed to help.
By
that time, the British government had one of the highest national death
tolls globally, having dragged its feet to impose lockdown
restrictions, shown reluctance to enforce rules and following futile
attempts to track and trace the spread of the virus. Its border was also
still wide open, and the government was throwing money at a rotating
cast of private sector consultants to secure basic personal protective
equipment (PPE) -- an effort that appeared more successful at generating
controversy than securing supplies.
But
the government's foresight in backing coronavirus vaccines has turned
into one of the most surprising success stories of the pandemic.
Despite
its widely criticized pandemic response, which has led to more than
117,000 deaths and more than 4 million coronavirus cases to date, the UK
has now administered 15 million coronavirus vaccine
doses -- a target set by the government to reach everyone in its top
four priority groups by February 15. The groups include everyone over
70, frontline health and social care workers, those living in care homes
and the clinically extremely vulnerable.
This total is more than Germany, France, Italy, Spain, Poland and Belgium combined. The UK has the third-highest vaccination rate worldwide behind Israel and the UAE.
Nadhim
Zahawi, the UK's minister for Covid-19 vaccine deployment, confirmed
the goal had been accomplished a day early in a post on Twitter Sunday.
"We will not rest till we offer the vaccine to the whole of phase 1,"
Zahawi wrote, referring to the priority groups set out by the
government.
UK Prime Minister Boris Johnson celebrated the moment, calling it a "significant milestone" and an "extraordinary feat."
"In
England I can now tell you we have now offered jabs to everyone in the
first four priority groups, the people most likely to be severely ill
from Coronavirus, hitting the first target we set ourselves," he wrote
on Twitter.
The British government also plans to give a first dose to the remaining risk groups and adults over 50 by the end of April.
Across
the country, soccer stadiums, horse racing tracks, cathedrals and
mosques are being used as mass vaccination sites. And through the
National Health Service (NHS), the government can reach almost every
person in the country to schedule a vaccination appointment.
In
the southern English town of Basingstoke, a working fire station is
being used for vaccinations. To accommodate the program, engines have
been moved outdoors, emergency deployment routes have been overhauled
and a small army of soldiers, firefighters, volunteers and nurses have
moved in.
"It
feels like a wartime effort," says Mark Maffey, the NHS architect who
led the transformation of the fire station and three other vaccination
sites in the area.
Big bets on 'longshot' vaccines
The centralized NHS is key to getting shots in arms, but it was an early series of big bets on then-unproven vaccines that really vaulted the UK ahead of the global pack.
Cautious
not to repeat its PPE-purchasing mistakes and unwilling to rely solely
on public servants who lacked expertise in vaccine procurement,
Britain's Chief Scientific Adviser Patrick Vallance pushed Downing
Street to bring in outside experts to form the vaccine taskforce.
On
paper, the unusual combination of public servants and current and
former industry insiders seems like a recipe for conflicts of interest,
but they were accountable to ministers and government auditors, explains
Bates, who left the committee last month.
The
taskforce was quick to get behind a vaccine being developed by a group
of scientists at the University of Oxford who had been working on a shot
for the Middle East Respiratory Syndrome -- a disease caused by another
type of coronavirus -- before shifting their focus to Covid-19. It
wasn't long before a vaccine was developed, but the challenge would be
getting it manufactured on an industrial scale, which is where AstraZeneca came in.
The
British-Swedish pharmaceutical company was chosen because of its
iron-clad commitment to prioritize the UK market, which, according to
both parties, involved providing all doses made in the UK to the British
government, and only exporting doses once the country had been
supplied. In exchange, the UK government agreed to invest heavily in the
vaccine's manufacture.
"I
wasn't going to settle for a contract that allowed the Oxford vaccine
to be delivered to others around the world before us," Health Secretary
Matt Hancock told UK radio station LBC earlier this month.
Of
the more than 100 vaccines in development worldwide at the time, the
taskforce short-listed around 20 based on how quickly they could be
trialled and made available. Ultimately, they chose seven based on the
makers' ability to scale up production for the UK. Those seven included
the three that have been approved to date by Pfizer/BioNTech, Moderna
and Oxford/AstraZeneca. Two others from Novavax and Johnson &
Johnson have also shown promise in Phase 3 trials published last month.
Bates
says bureaucratic hoops were kept to a minimum. "I think having a small
group makes decisions easier and faster," he said, adding that Bingham
"having the hotline to the Prime Minister also made sure that the chains
of command were very short at key moments when decisions were made."
Going it alone
The
speed at which the UK has been able to approve and administer vaccines
is due in part to the country's decision to go it alone, rather than
joining the European Union's procurement effort. When the EU offered the UK the chance to join forces, it insisted it drop any ongoing contract discussions.
"That
didn't feel like the right thing to do, so the UK didn't do it," said
Bates, estimating the decision "probably gave us at least three months'
advance work, which is proving invaluable."
The
UK's decision not to join Europe's procurement strategy was
controversial. Last March, Martin McKee, a European health professor at
the London School of Hygiene and Tropical Medicine, predicted in the
Guardian newspaper that Britain would pay more and get fewer vaccines by
going it alone.
"The
timing of the pandemic ... could provide an opportunity to reflect on
whether an isolationist ideology really is such a good idea," wrote
McKee.
His
view has since changed. "I fully concede that I was wrong on this one,"
McKee told CNN. "I give full credit to Kate Bingham ... she did very
well."
But Britain's head start left Europe frustrated and lagging behind -- prompting a diplomatic spat across the English Channel. At one point in January, EU leaders even threatened to restrict exports of vaccines produced in Europe to even the score.
Last
month AstraZeneca clarified that it never contractually promised Europe
it would be supplied with doses at the same rate as the UK. "Basically,
we said we're going to try our best," the company's CEO Pascal Soriot explained to Italian newspaper La Repubblica.
McKee
believes the UK's success is also due to the well-organized and
centralized NHS system, giving the country an advantage many other
countries lack. The fire station in Basingstoke is able to inject more
than 1,000 vaccine doses per day. Nationwide, daily injections have at
one point topped 600,000. NHS staff, emergency services and ordinary
volunteers are all starting to see their efforts pay off.
The
firefighters now trained to give shots in Basingstoke work under Steve
Apter, the deputy chief fire officer for the county of Hampshire. Last
summer Apter's mother was hospitalized with Covid-19 symptoms and later
died of pneumonia. Her test eventually came back negative, but her
symptoms meant she was isolated for days, unable to have her family at
her bedside.
"The
sense of helplessness was overwhelming," he recalled. He is proud of
how the fire service is contributing to the vaccination effort and can't
help but feel a sense of national pride too.
"I've never experienced such open sense of shared purpose than we're seeing now."
A
previous version of this story stated that Steve Bates was not paid for
his role on the taskforce. It has been updated to clarify that the UK
government did compensate Bates' organization for his time spent on the
taskforce.
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